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2-Methyl-AP-237, also known as 2-Methyl-N-(2-phenylethyl)-AP-237, is a synthetic cannabinoid receptor agonist that belongs to the AP-237 family. It is structurally similar to AP-237 but contains a 2-methyl group at the N-1 position. This modification is believed to enhance the potency and selectivity of 2-Methyl-AP-237.

Chemical Structure

The chemical structure of 2-Methyl-AP-237 is as follows:

Chemical Structure of 2-Methyl-AP-237


2-Methyl-AP-237 is an agonist of the CB1 receptor, where it binds to and activates specific sites on this receptor. By doing so, it triggers an array of biological responses associated with cannabinoid signaling. These effects can include analgesia, anxiolytic effects, and alterations in mood, appetite, and cognitive function.

Metabolism and Pharmacokinetics

The metabolism and pharmacokinetics of 2-Methyl-AP-237 are not fully understood. However, like other synthetic cannabinoids, it is suspected that it may be metabolized by enzymes in the liver and excreted in the urine. The rate and extent of metabolism can vary depending on the individual’s age, sex, and overall health.

Toxicity and Side Effects

The toxicity and side effects of That have not been extensively studied. However, like other synthetic cannabinoids, it has been associated with a range of adverse effects, including anxiety, paranoia, nausea, vomiting, and hypertension. These effects can be more severe in individuals with pre-existing mental health disorders or who are taking certain medications.

Legal Status

2-Methyl-AP-237 is illegal in most countries, including the United States, Canada, and the European Union. It is classified as a Schedule I controlled substance due to its potential for abuse and addiction. The sale, distribution, and possession of that can be prosecuted under drug laws.


2-Methyl-AP-237 is a synthetic cannabinoid receptor agonist that belongs to the AP-237 family. It exhibits similar pharmacological properties to AP-237 but may be more potent and selective. However, its metabolism and toxicology have not been thoroughly investigated. It is illegal in most countries and carries the risk of adverse effects when misused.

Additional information


10 Gram, 25 Grams, 50 Grams, 100 Grams, 250 Grams, 500 Grams, 1000 Gram


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