Description

N-Desethyl Isotonitazene

N-desethyl Isotonitazene is a synthetic opioid analgesic that is widely used in pharmaceutical products. It is a secondary metabolite of Isotonitazene and acts as a potent opioid receptor agonist. N-desethyl Isotonitazene possesses similar pharmacological properties to its parent compound, but with lower potency.

Chemical Structure

The chemical structure of N-desethyl Isotonitazene can be found in the following diagram:

Chemical Structure of that is:

Pharmacological Properties

They has similar pharmacological properties to its parent compound Isotonitazene. It acts as a mu-opioid receptor agonist, exerting analgesic effects and reducing the perception of pain. However, its potency is lower than Isotonitazene, making it less susceptible to abuse and misuse.They  also exhibits some selectivity towards other opioid receptor subtypes, including delta and kappa receptors.

Clinical Use

They are primarily used in pharmaceutical formulations to enhance the potency and efficacy of other opioids. It is often combined with opioid analgesics, such as oxycodone or methadone, to enhance their analgesic properties and reduce the risk of tolerance and dependence. it is also used in pain management treatments, specifically in neuropathic pain conditions, where the effectiveness of opioids may be limited.

Toxicity and Safety

N-desethyl Isotonitazene has a moderate toxicity profile similar to its parent compound Isotonitazene. It can cause respiratory depression, sedation, and constipation. It is important to administer that cautiously and under the supervision of healthcare professionals to avoid potential adverse effects.

Conclusion

N-desethyl Isotonitazene is a synthetic opioid analgesic that exhibits pharmacological properties similar to its parent compound . It is commonly used in pharmaceutical products to enhance the analgesic effects of other opioids and in the management of neuropathic pain conditions. However, It should be used cautiously and with appropriate dosage to minimize the risk of adverse effects.