Deoxymethoxetamine (DMXE)



Deoxymethoxetamine (DMXE)

Deoxymethoxetamine (DMXE) is a synthetic dissociative anesthetic that belongs to the arylcyclohexylamine class of drugs. It was initially synthesized by scientists in the 1980s and has since gained popularity as a research chemical and illicit substance. DMXE is primarily used as a recreational drug due to its hallucinogenic and dissociative effects.

Chemistry and Structure

DMXE belongs to the phenethylamine and amphetamine classes of compounds, sharing structural similarities with both classes. Its chemical structure consists of a phenyl ring connected to an amphetamine group via an ethyl chain. This structure is responsible for DMXE’s pharmacological properties.


DMXE acts as a NMDA receptor antagonist, blocking the neurotransmitter glutamate from binding to its receptors. This leads to a range of hallucinogenic and dissociative effects, similar to those observed with other dissociative anesthetics such as ketamine and PCP.


The subjective effects of DMXE can vary depending on dosage and individual factors such as tolerance and susceptibility. Users commonly report experiencing distortions of perception, altered reality, and dissociation from their bodies. DMXE can also induce feelings of euphoria, increased heart rate and blood pressure, and heightened alertness.

Risks and Side Effects

The recreational use of DMXE carries numerous risks and potential side effects. Prolonged use can lead to addiction and dependence, as well as various psychological and physiological problems. Common side effects include anxiety, paranoia, hallucinations, and addiction. DMXE can also have negative effects on cognitive functioning, memory, and mental health.

Legality and Regulation

DMXE is not scheduled under international drug control conventions, making its legal status dependent on individual countries. However, due to its potential abuse and dangerous effects, many countries have implemented regulations to restrict its production and distribution. Users should familiarize themselves with the legal implications of using or possessing DMXE in their jurisdiction.


Deoxymethoxetamine (DMXE) is a synthetic dissociative anesthetic that has gained attention for its hallucinogenic and dissociative effects. While DMXE is often used recreationally, its potential risks and side effects make it a dangerous substance. It is important to stay informed about the legal status and regulations surrounding DMXE to ensure the safety of oneself and others.

Additional information


5 grams, 10 grams, 15 grams, 25 grams, 50 grams, 100 grams, 250 grams, 500 grams, 1kg


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