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7-Hydroxymitragynine is a natural alkaloid found in the plant Mitragyna speciosa. It belongs to the class of chemical compounds known as opioids, which are derives from the opium poppy plant. 7-Hydroxymitragynine is knowns for its psychoactive and analgesic effects, and it has emerges as a potential therapeutic agent for various conditions.

Chemical Structure

The chemical structure of 7-hydroxymitragynine is showing below:

Chemical structure of 7-hydroxymitragynine

Mechanism of Action

The mechanism of action of 7-hydroxymitragynine is not fully understand. However, it is believes that it interacts with the μ-opioid receptors in the brain, which are the receptors involving in mediating the effects of opioids. This interaction leads to analgesia and a sense of euphoria, similar to opioids such as morphine.


Some of its known effects include:

1. Analgesic: 7-Hydroxymitragynine has been shown to relieve pain, making it a potential alternative to opioids for pain management.

2. Antidepressant: It has been shown to exhibit antidepressant-like effects, potentially offering relief from symptoms of depression and anxiety.

3. Antitussive: It has demonstrated antitussive properties, making it useful in treating cough and respiratory disorders.

4. Anti-inflammatory: It has shown anti-inflammatory properties, suggesting its potential use in the treatment of inflammation and related conditions.

5. Anxiolytic: It has demonstrated anxiolytic effects, reducing feelings of anxiety and promoting calmness and relaxation.

Safety Concerns

While 7-hydroxymitragynine has shown promise as a therapeutic agent, it is important to consider its potential safety concerns. Some of the potential risks associated with its use include:

1. Addiction potential: Like other forms of opioids, 7-hydroxymitragynine may have addiction potential, especially when used recreationally.

2. Respiratory depression: It can cause respiratory depression, which can be dangerous in individuals with respiratory conditions or who misuse the substance.

3. Tolerance and dependence: Regular use can lead to tolerance and dependence, making individuals dependent on higher doses to achieve the same effects.

4. Hepatotoxicity: In rare cases, 7-hydroxymitragynine has been associated with liver damage, making it important for proper use and monitoring of liver function.


7-Hydroxymitragynine is a naturally occurring alkaloid with potential therapeutic benefits. However, it is important to consider the potential safety concerns associated with its use, especially when not under the supervision of a medical professional. Further research is need to fully evaluate its safety and efficacy, as well as to establish appropriate guidelines for its clinical use.

Additional information


100 µg/ml, 200 µg/ml, 300 µg/ml, 400 µg/ml, 1Kg


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